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In clinical trials, Fosamax significantly increased bone mineral density (closely related to bone strength) at the spine (8.

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The modified intention-to-treat analysis included all women with measurements at base line, year 7, and at least one subsequent year in which a study drug was given; data from the last evaluation were carried forward in women who did not complete year 10.

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During the 1990s, Fosamax was widely used to treat osteoporosis and other conditions that weaken bones, and it's estimated that millions of men and women across the world have taken Fosamax.

INTERSEX AND GENDER IDENTITY DISORDERS: Side Effects of Pharmacotherapy on Bone with Long-Acting Gonadorelin Agonist Triptorelin for Paraphilia.

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According to the prescribing information for Fosamax (alendronate), one of the side effects of bisphosphonates which may occur is called osteonecrosis of the jaw (ONJ).

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